FARM2100 – Medicinal Chemistry
Course description
Schedule, syllabus and examination date
Course content
The subject deals with the chemistry of the drug substances and how the chemical properties of the drug substances affect the biological profile of the drugs. The course deals with topics such as synthesis, stability and structural activity for the most important drug groups.
Learning outcome
After completing the course:
- you will have broad knowledge of general principles in medicinal chemistry and specific knowledge of the medicinal chemistry related to the most important drug groups.
- you will have broad knowledge of the preparation (including synthesis), chemical properties, stability, metabolism and structural activity (SAR) of drug substances.
- you should, based on the chemical structure of a drug substance, be able to apply principles in drug chemistry and understand possible biological properties in relation to interaction with target molecules, route of administration, formulation, biodistribution, metabolism and excretion.
- you should, based on the basis of interdisciplinary drug-related texts such as "Felleskatalog"-text, be able to explain the topics that are directly chemically related and should also be able to actively participate in discussion of other drug-related topics where these may be related to the structure and chemical properties of the drug substances.
- you can evaluate and convey results from laboratory exercises in a scientific report.
Admission to the course
The course is only available to students enrolled at the Department of Pharmacy at the University of Oslo.
Pregnant and breastfeeding:?This course uses chemicals in laboratory exercises that can be harmful to pregnant and breastfeeding women (fetus/child). No exemption?from the laboratory exercises is?granted as these must be approved to fulfill the learning outcomes in the course. Students can apply for facilitation; see?Special needs and leave of absence.?For more information, contact?the study administration at the Department of Pharmacy.
Formal prerequisite knowledge
- FARM1100 – Pharmaceutical Chemistry
- FARM1110 – Pharmacology, Physiology and Cell Biology 1
- FARM1120 – Social Pharmacy
- FARM1130 – Pharmaceutically Based Organic Chemistry
- FARM1140 – Pharmacology, Physiology and Cell Biology 2
- FARM1150 – Pharmaceutical Based Biochemistry
- The compulsory HSE-courses HMS0501 – Safety and Physical Environment, HMS0502 – Positive Learning Environment, HMS0503 – Laboratory Safety, HMS0506 – Patient Clinic Safety and HMS0507 – Fire Safety required for students at the 5-year Master`s Programme in Pharmacy.
Course exemption:?Laws and regulations describing the overall learning outcome regulate the Pharmacy programme.?Exemptions are only granted if all learning outcomes in the course are covered.
The information about overlaps is not complete.
Overlapping courses
- 5 credits overlap with FRM2000 – Drugs and How They Work Part II (discontinued).
- 5 credits overlap with FARM2105 – OE i legemiddelkjemi (discontinued).
Teaching
- Approx. 30 hours of lectures
- Approx. 20 hours of colloquia
- Approx. 20 hours laboratory course (compulsory)
- active participation in preparing and presenting a mini-lecture together with other students (compulsory)
Compulsory participation in the course must be completed and approved and compulsory submissions must be approved to pass the exam.?Read more about what applies in the event of absence from compulsory activities.
As?the?teaching involves laboratory and/or field work, you should consider taking out a separate travel and personal risk insurance.?Read about your insurance cover as a student.
Access to teaching:?A student who has completed compulsory instruction and coursework and has had these approved, is not entitled to repeat that instruction and coursework. A student who has been admitted to a course, but who has not completed compulsory instruction and coursework or had these approved, is entitled to repeat that instruction and coursework, depending on available capacity.
Completed and approved compulsory instruction and coursework are valid for 3 years.
Examination
Final written exam, which counts 100?% towards the final?grade.?
This course has compulsory exercises that must be approved before you can sit the final?exam.
Examination support material
The periodic table of the elements.
Casio FX-991EX calculators are handed out to all exam candidates at the beginning of the exam.
Language of examination
The examination text is given in Norwegian. You may submit your response in Norwegian, Swedish or Danish.
Grading scale
Grades are awarded on a scale from A to F, where A is the best grade and F is a fail. Read more about the grading system.
Resit an examination
This course offers both postponed and resit of examination. Read more:
More about examinations at UiO
- Use of sources and citations
- Special exam arrangements due to individual needs
- Withdrawal from an exam
- Illness at exams / postponed exams
- Explanation of grades and appeals
- Resitting an exam
- Cheating/attempted cheating
You will find further guides and resources at the web page on examinations at UiO.