BIOS9912 – Eukaryotic Transcription Factors - Structures, Function, Regulation
Course description
Course content
The course focuses on current understanding of the structure and function of eukaryotic transcription factors. Topics covered are: promoters, RNA polymerase II, general transcription factors and coactivators, the role of chromatin structure in transcription, elongation control and the mechanisms of gene activation, as well as nuclear organization. Connections between oncogenesis and transcription will also be addressed.
Learning outcome
After completing the course you are expected to have knowlegde about and an overview of the research front in subjects such as:
- understand central aspects of the complex structure and function of the transcription apparatus which regulates the expression of genes in eucaryotic cells. ?
- understand?resent research in the field of eukaryotic transcription.
- expertise in conveying a subject by giving a presentation for other participants on the course.
Admission to the course
PhD candidates from the University of Oslo should apply for classes and register for examinations through?Studentweb.
If a course has limited intake capacity, priority will be given to PhD candidates who follow an individual education plan where this particular course is included. Some national researchers’ schools may have specific rules for ranking applicants for courses with limited intake capacity.
PhD candidates who have been admitted to another higher education institution must?apply for a position as a visiting student?within a given deadline.
Applicants are ranked by the following criteria:
- Master students and PhD candidates at the MN faculty who have the course as part of the approved curriculum.
- Students with admission to single courses on master’s level and exchange students
Applicants are ranked by credits in each group; all applicants within 1st rank before applicants in 2nd etc. If admission is limited to a fixed number of participants, admission will be decided by drawing lots for students who are ranked equally
Formal prerequisite knowledge
Admission to a PhD program
Recommended previous knowledge
emne.BIOS3900, BIOS4010 – Methods in Molecular Biology and Biochemistry I, BIOS4020 – Methods in Molecular Biology and Biochemistry II or corresponding knowledge
Overlapping courses
- 10 credits overlap with BIOS5912 – Eukaryotic Transcription Factors - Structures, Function, Regulation.
- 10 credits overlap with MBV4230 – Eukaryotic Transcription Factors - Structures, Function, Regulation (continued).
- 10 credits overlap with MBV9230 – Eukaryotic Transcription Factors - Structures, Function, Regulation (continued).
Teaching
- Lectures
- Seminars with a 15 minutes presentations of a scientific article for the other students. As part of the teaching, all PhD candidates will hold an individual presentation of a scientific article for the other participants on the course.
Attendance is mandatory for the first lecture. This also applies to those on the waiting list. You will lose your seat on the course if documentation for absence is not provided to the student administration studieinfo@ibv.uio.no prior to the first lecture.
Examination
- Final written exam, which counts 100 % towards the finale grade.?
This course has mandatory assignments that must be approved before you can sit the finale exam.
An individual presentation of a research article must be approved before the exam.
Optional oral exam depending on the number of participants.?
It will also be counted as one of the three attempts to sit the exam for this course, if you sit the exam for one of the following courses:?emne:MBV4230, MBV9230 – Eukaryotic Transcription Factors - Structures, Function, Regulation (continued), BIOS5912 – Eukaryotic Transcription Factors - Structures, Function, Regulation
Examination support material
No examination support material is allowed.
Grading scale
Grades are awarded on a pass/fail scale. Read more about?the grading system.
Resit an examination
This course offers both postponed and resit of examination. Read more:
More about examinations at UiO
- Use of sources and citations
- Special exam arrangements due to individual needs
- Withdrawal from an exam
- Illness at exams / postponed exams
- Explanation of grades and appeals
- Resitting an exam
- Cheating/attempted cheating
You will find further guides and resources at the web page on examinations at UiO.