KJM 3200 – Required Reading (Pensum), Fall 2019
? John McMurry: “Organic Chemistry” 9. ed. as specified below.
? Lise-Lotte Gundersen “KJM 3200. Organic Chemistry II. Laboratory manual”, Fall 2018
After completing the introductory course in organic chemistry (KJM1111) as well as KJM3200, the intention is
that the student shall master the subjects presented in McMurry except most metabolic pathways, polymer
chemistry, (and other parts about polymer chemistry and biochemistry elsewere in the book), and the
spectroscopy covered by KJM3000.
Required reading from "McMurry 9. ed"
| Topic | Chapter | Title | Ca.No of pages |
|---|---|---|---|
| Dienes | 14 | Conjugated compounds and UV spectroscopy | 13 |
| 14.1 | Stability of conjugated dienes: MO theory | ||
| 14.2 | Electrophilic addition to conjugated dieles: Allylic carbocations. | ||
| 14.3 | Kinetic vs thermodynamic control of reactions. | ||
| 14.9 | Conjugation, color, and the chemistry of vision | ||
| Organometallics | 10 | Organohalides | 3 |
| 10.7 | Organometallic coupling reaction | ||
| Reactions of alkohols and phenols |
17 | Alcohols and Phenols | 7 |
| 17.8 | Protection of alcohols | ||
| 17.9 | Phenols and their use | ||
| 17.10 | Reactions on phenols | ||
| Reactions of ethers, epoxides, thiols and sulfides |
18 | Ethers and Epoxides; Thiols and Sulfides | 19 |
| 18.1 | Names and properties of ethers | ||
| 18.2 | Preparing ethers | ||
| 18.3 | Reactions of ethers: Acidic cleavage | ||
| 18.5 | Cyclic ethers: Epoxides | ||
| 18.6 | Reactions of epoxides: Ring-opening | ||
| 18.7 | Crown ethers | ||
| 18.8 | Thiols and sulfides | ||
| Reactions of aldehydes and ketone |
19 | Aldehydes and Ketones: Nucleophilic addition reactions | 5 |
| 19.3 | Conjugate nucleophilic addition to α,β unsaturated aldehydes and ketones | ||
| Carbonyl α- substitutions |
23 | Carbonyl condensation reactions (the whole chapt. except 23.13) | 13 |
| 23.7 | The Claisen condensation reaction | ||
| 23.8 | Mixed Claisen condensation | ||
| 23.9 | Intramolecular Claisen condensation: The Dieckmann cyclization | ||
| 23.10 | Conjugate carbonyl addition: The Michael reaction | ||
| 23.11 | Carbonyl condensation with enamines: The Stork reaction | ||
| 23.12 | The Robinson annulation reaction | ||
| Aromatic compounds |
16 | Chemistry of benzene: Electrophilic aromatic substitution | 4 |
| 16.6 | Nucleophilic aromatic substitution | ||
| 16.7 | Benzyne | ||
| Amines & Heterocycles |
24 | Amines and heterocycles | 23 |
| 24.6 | Synthesis of amines (from p 800) | ||
| 24.7 | Reactions of amines | ||
| 24.8 | Reactions of arylamines | ||
| 24.9 | Heterocyclic amines | ||
| Carbohydrates | 25 | Biomolecules: Carbohydrates | 30 |
| 25.1 | Classification of carbohydrates | ||
| 25.2 | Depicting carbohydrate stereochemistry: Fisher projections | ||
| 25.3 | D,L Sugars | ||
| 25.4 | Configaration of aldoses | ||
| 25.5 | Cyclic structures of monosaccharides: Anomers | ||
| 25.6 | Reactions of monosaccharides | ||
| 25.8 | Disaccharides | ||
| 25.9 | Polysaccarides and theirs synthesis | ||
| Amino acids, peptides etc |
26 | Biomolecules: Amino acids, peptides and proteins (the whole chapt. 26 except 26.9-26.11) |
23 |
| Lipids, terpenoids etc |
27 | Biomolecules: Lipids (the whole chapt. ) | 30 |
| Nucleic acids |
28 | Biomolecules: Nucleic acids | 9 |
| 28.1 | Nucleotides and Nucleic acids | ||
| 28.2 | Base pairing in DNA: The Watson-Crick Model | ||
| 28.7 | DNA synthesis | ||
| Pericyclic reactions |
8 | Alkenes: Reactions and Synthesis | 3 |
| 8.9 | Addition of carbenes to alkenes: Cyclopropan e synthesis | ||
| 14 | Conjugated compounds and UV spectroscopy | 5 | |
| 14.4 | The Diels Alder cycloaddition reaction | ||
| 14.5 | Charactheristics of the Diels Alder reaction | ||
| 18 | Ethers and epoxides; thiols and sulfides | 2 | |
| 18.4 | Reactions of ethers: Claisen rearrangement | ||
| 30 | Orbitals and organic chemistry: Pericyclic reactions (the whole chapt.) | 18 | |
| Total No of pages* | 207 |
*The nummer of pages doesnot include exercises at the end of the chapters and "Something extra"