KJM9230 – Bioactive Molecules
Course description
Schedule, syllabus and examination date
Course content
This is an advanced course in organic chemistry emphasizing the chemistry of low molecular weight bioactive molecules, including natural products, their biological mechanisms of action, ADME properties, and general aspects of drug design. The course deals with the organic chemistry of important drug classes and bioactive natural substances. Synthesis/biosynthesis, mechanism of action, bioavailability, and stability for selected classes of drugs are discussed. The course is suitable for Ph.D. candidates in organic chemistry and related areas.
Learning outcome
After completing the course, you:
- can recognize the important classes of low molecular weight natural products and are?able to describe their biosynthetic pathways
- are familiar with general aspects of drug design
- understand and are?able to explain how drugs can exert their activity by interaction with receptors and enzyme
- are familiar with the use of peptides, proteins, and mimics as drugs
- understand and are?able to explain the important pathways for the metabolism of xenobiotics
- know the important classes of antibacterial incl antimycobacterial, antifungal, antiprotozoal, and antiviral drugs, and understand their mechanisms of action
- know the important classes of anticancer drugs and understand their mechanisms of action
Admission to the course
PhD candidates from the University of Oslo should apply for classes and register for examinations through?Studentweb.
If a course has limited intake capacity, priority will be given to PhD candidates who follow an individual education plan where this particular course is included. Some national researchers’ schools may have specific rules for ranking applicants for courses with limited intake capacity.
PhD candidates who have been admitted to another higher education institution must?apply for a position as a visiting student?within a given deadline.
Recommended previous knowledge
KJM3200 – Organic Chemistry II and partly KJM1140 – Biochemistry 1 for Chemists or BIOS1130 – Biokjemi 1
Overlapping courses
- 10 credits overlap with KJM5230 – Bioactive Molecules.
Teaching
The teaching includes:
- 20 hours of lectures
- 10 hours of group exercises
Attendance at the first lecture is mandatory. You will lose your place in the course if you do not inform the student administration at the Department of Chemistry before the first lecture starts.
Within August 10th / January 10th, international students must inform the Department of Chemistry if English teaching is requested.
Examination
- Final oral exam, which counts 100 % towards the final grade.
It will also be counted as one of the three attempts to sit the exam for this course, if you sit the exam for one of the following courses: KJM5230 – Bioactive Molecules
Grading scale
Grades are awarded on a pass/fail scale. Read more about the grading system.
Resit an examination
Students who can document a valid reason for absence from the regular examination are offered a?postponed exam?at the beginning of the next semester.
New examinations?are offered at the beginning of the next semester for students who do not successfully complete the exam during the previous semester.
We do not offer a re-scheduled exam for students who withdraw during the exam.
More about examinations at UiO
- Use of sources and citations
- Special exam arrangements due to individual needs
- Withdrawal from an exam
- Illness at exams / postponed exams
- Explanation of grades and appeals
- Resitting an exam
- Cheating/attempted cheating
You will find further guides and resources at the web page on examinations at UiO.