MF9310 Methods in intervention epidemiology: (Evidence Based Medicine) 22nd - 25th February 2010
 

Location:         Auditorium, Frederiks Holsts hus, Ullevål Universitetssykehus, Kirkeveien 166 

Course organizers:  Akhtar Hussain, Lien Diep and Torkel Snelling

Course programme:

Monday 22.02.2010
09.00 - 09.45     Registration & Course introduction (AH & TS)
10.00 - 10.45     Evidence Based Medicine (EBM) Concepts - Appraisal of Literature and Concepts of Systematic Review (TS)
11.00 - 11.45     Concepts of Research Design (AH)
11.45 - 13.00     Lunch
13.00 - 14.45     Divide into groups and choose group moderator & Choose tentative research topic (TC)
15.00 - 15.45     Presentation of tentative Research Topic (TC)

Tuesday 23.02.2010
09.00 - 10.45     Research design in intervention studies. Methods and types of clinical trials: uncontrolled trials, historical controls, concurrent non-randomized controls, randomized clinical trial cross over trials AH
11.00 - 11.45     Undertaking a literature Review (TS)
11.45 - 13.00     Lunch
13.00 - 13.45     Appraising the literature and systematic Review (TS)
14.00 - 15.45     Diagnosis and its challenges in intervention studies, sensitivity, specificity (PPV and NPV) Agreement and kappa score. Measuring attributable risk for intervention/preventive measures. (AH)
                            Continue working on a intervention protocol

Wednesday 24.02.2010
09.00 - 10.45     Introduction to randomized Control Trial (RCT). Epidemiological research design for intervention studies continue with a special focus to Randomization, Concealment of allocation, Blinding and placebos (Haakon Meyer)
11.00 - 11.45     Present Literature Review on Research Topic (TS)
12.00 - 13.00     Lunch
13.00 - 13.45     Research Confounding and Bias, Sample Selection & sample size (AH)
14.00 - 14.45     Finalize research Protocol
15.00                  Presentation of Intervention Protocols

Thursday 25.02.2010
Responsible: Lien Diep
Mathematical models for the analysis of cohort studies and intervention outcomes (Lien)

09.00     Summary statistics, presenting data as graphs and tables.
10.00     Data lab.
12.00     Lunch
13.00     Odds ratio and relative risk revisited. Uncertainties and tests
15.00     Data lab.
16.00     End

Friday 26.02.2010
Responsible: Lien Diep
09.00     Logistic regression: confounding and interaction
12.00     Lunch
13.00     Data-lab: Logistic regression and test
15.00     Evaluation
16.00     End