Personalized Gene Correction for Inborn Errors of Immunity

Are you passionate about research on gene editing technologies? Join our lab for a one-year Master’s project focused on personalized gene correction for inborn errors of immunity—a group of genetic disorders affecting the immune system that can lead to infections, allergies, autoimmune conditions, and cancer. 

About the project

Our lab is developing a platform to correct patient-specific mutations in T-cells and blood stem cells, with the ultimate goal of reinfusing these gene-corrected cells as a form of autotransplant therapy. This work places you at the intersection of translational immunology, gene therapy, and regenerative medicine. 

What you'll do

Depending on your interests and background, your project may include: 

  • Demonstrating correction of genetic mutations in immune cells 

  • Participating in animal experiments 

  • Characterizing edited cells with different techniques (e.g., droplet digital PCR, flow cytometry) 

  • Optimizing cell culture systems to support growth of immune-deficient cells 

You will be supervised by a senior scientist or an experienced PhD student in a dynamic, international research environment. 

Start Dates 

We accept two Master’s students per year, with start times between June and August. 

Why Join Us? 

  • Hands-on experience with CRISPR gene editing and cell therapy 

  • Exposure to a broad range of immunodeficiencies and molecular techniques 

  • Excellent track record: our Master’s alumni have quickly secured positions in both academia and industry 

How to Apply 

If you’re interested, please contact: 

  • Emma Haapaniemi (Group Leader) emma.haapaniemi@ncmbm.uio.no 

Send your CV and a short motivation letter outlining your interests and preferred start date. 

Publisert 1. juli 2025 10:24 - Sist endret 1. juli 2025 10:24

Veileder(e)

Omfang (studiepoeng)

60