FARM1140 ¨C Pharmacology, Physiology and Cell Biology 2

Course content

The course "Pharmacology, physiology and cell biology 2" provides an introduction to the structure and function of some of the body?s organ systems (gastrointestinal, heart and circulation, lungs and kidneys). Anatomy and physiology are basis for understanding pathophysiology and mechanisms of action of drugs within the aforementioned organ systems. Key principles for interaction between drugs and target molecules (eg receptors, enzymes), intracellular mediators and signaling pathways are addressed.

Learning outcome

After completing the course you will be able to:

• account for the blood's chemical composition (proteins and electrolytes), the various blood cell types, cascade systems and the structure and function of the immune system.
• explain how the human body is built, be able to describe the anatomy of some organ systems (gastrointestinal tract, heart and circulation, lungs, kidneys) and how these function.
• account for the molecular mechanisms of action for drugs linked to the mentioned organ systems, including target molecules and signaling pathways.
• account for the connection between physiology, pathophysiology and the drug's interaction with the target molecule in selected therapeutic areas (anaemias, allergies, gastrointestinal diseases and diseases of the respiratory tract), as well as evaluate drug treatment of these diseases.
• convey information about drug use, and drugs' molecular and cellular mechanisms of action in an understandable way.
• describe certain test systems and carry out simple laboratory experiments under guidance to examine cells/tissues and drug effects.
• calculate concentrations and use different nomenclatures.
• assess results from simple experiments and understand the relationship between drug concentration, effect and side effects.

Admission to the course

The course is only available to students enrolled at the Department of Pharmacy at the University of Oslo.

Formal prerequisite knowledge

• Approved the compulsory parts of FARM1110 ¨C Pharmacology, Physiology and Cell Biology 1.
• Passed the compulsory HSE courses HMS0501 ¨C Safety and Physical Environment, HMS0502 ¨C Positive Learning Environment, HMS0503 ¨C Laboratory Safety, HMS0506 ¨C Patient Clinic Safety and HMS0507 ¨C Fire Safety required for students at the 5-year Master`s Programme in Pharmacy.

Course exemption: Laws and regulations describing the overall learning outcome regulate the Pharmacy Programme. Exemptions are only granted if all learning outcomes in the course are covered.?

Recommended previous knowledge

• FARM1110 ¨C Pharmacology, Physiology and Cell Biology 1

Overlapping courses

• 8 credits overlap with FARM2190 ¨C OE i fysiologi, farmakologi og lovkunnskap (discontinued).
• 7 credits overlap with FARM2290 ¨C OE i fysiologi, farmakoterapi og lovkunnskap (discontinued).
• 4 credits overlap with FRM3020 ¨C Use of Drugs, Part II (discontinued).
• 3 credits overlap with FARM3190 ¨C OE i fysiologi, farmakoterapi, legemiddelanalyse og farmakognosi (discontinued).

Teaching

Lectures and student active teaching, including flipped classroom/group work/colloquiums, project assignment, laboratory exercises and simulation of physiological processes.

• 1 hour compulsory introductory lecture
• 30 hours lectures
• 3 hours compulsory pre-laboratory lectures?
• 9 hours laboratory exercises with submission of 3 individual laboratory reports - compulsory
• Project assignment - compulsory project assignment
• 30 hours colloquia / flipped classroom - compulsory 50% attendance
• Compulsory attendance at pharmacy- and communication colloquia

Compulsory participation in the course must be completed and compulsory submissions must be approved/passed in order to take the exam.

Read more about what applies in the event of absence from compulsory activities.

As?the?teaching involves laboratory and/or field work, you should consider taking out a separate travel and personal risk insurance. Read about your insurance cover as a student.

A student who has completed compulsory instruction and coursework and has had these approved, is not entitled to repeat that instruction and coursework. A student who has been admitted to a course, but who has not completed compulsory instruction and coursework or had these approved, is entitled to repeat that instruction and coursework, depending on available capacity.

Completed and approved compulsory instruction and coursework are valid for 3 years.

Passed compulsory assignments that are part of the exam are valid for 1 year (the year they were conducted).

Examination

• Final written exam, which counts approximately 80% towards the final grade

• 2 laboratory reports and project assignment, which count approximately 20 % towards the?final grade

The final written exam, laboratory reports and the project assignment must be passed to pass the exam. The final grade can be assessed subjectively.

Passed laboratory reports and project assignment that are part of the exam are valid for 1 year (the year they were conducted).

For admission to the final written exam the following must be approved/passed:

• 3 laboratory reports, participation in laboratory exercises and attending pre-laboratory lectures

• 1 project assignment

• 50 % attendance at colloquia

• attendance at pharmacy- and communication colloquia

• 1 hour compulsory introductory lecture

It is possible to take the exam up to 3 times. If you withdraw from the exam after the deadline or during the exam, this will be counted as an examination attempt.

It will also be counted as one of three attempts to sit the exam for this course, if you sit the exam for one of the following courses:

• FARM2190 ¨C OE i fysiologi, farmakologi og lovkunnskap (discontinued)

• FARM2290 ¨C OE i fysiologi, farmakoterapi og lovkunnskap (discontinued)

Examination support material

You will have access to a calculator in Inspera during exam.

Language of examination

The examination text is given in Norwegian. You may submit your response in Norwegian, Swedish or Danish.

Grading scale

Grades are awarded on a scale from A to F, where A is the best grade and F?is a fail. Read more about the grading system.

Resit an examination

This course offers both postponed and resit of examination. Read more:

• Illness at exams / postponed exams
• Withdrawal during an examination / Resitting an examination

More about examinations at UiO

• Use of sources and citations
• Special exam arrangements due to individual needs
• Withdrawal from an exam
• Illness at exams / postponed exams
• Explanation of grades and appeals
• Resitting an exam
• Cheating/attempted cheating

You will find further guides and resources at the web page on examinations at UiO.