BIOS5912 – Eukaryotic Transcription Factors - Structures, Function, Regulation
Course description
Course content
The course focuses on current understanding of the structure and function of eukaryotic transcription factors. Topics covered are: promoters, RNA polymerase II, general transcription factors and coactivators, the role of chromatin structure in transcription, elongation control and the mechanisms of gene activation, as well as nuclear organization. Connections between oncogenesis and transcription will also be addressed.
Learning outcome
After completing the course you are expected to have knowlegde about and an overview of the research front in subjects such as:
- understand central aspects of the complex structure and function of the transcription apparatus which regulates the expression of genes in eucaryotic cells. ?
- understand?resent research the field of eukaryotic transcription.
Admission to the course
Students admitted at UiO must?apply for courses?in Studentweb. Students enrolled in other Master's Degree Programmes can, on application, be admitted to the course if this is cleared by their own study programme.
Nordic citizens and applicants residing in the Nordic countries may?apply to take this course as a single course student.
If you are not already enrolled as a student at UiO, please see our information about?admission requirements and procedures for international applicants.
Applicants are ranked by the following criteria:
- Master students and PhD candidates at the MN faculty who have the course as part of the approved curriculum.
- Students with admission to single courses on master’s level and exchange students
Applicants are ranked by credits in each group; all applicants within 1st rank before applicants in 2nd etc. If admission is limited to a fixed number of participants, admission will be decided by drawing lots for students who are ranked equally
Recommended previous knowledge
BIOS3900 – Biochemistry 2, BIOS4010 – Methods in Molecular Biology and Biochemistry I, BIOS4020 – Methods in Molecular Biology and Biochemistry II??or corresponding knowledge.
Overlapping courses
- 10 credits overlap with BIOS9912 – Eukaryotic Transcription Factors - Structures, Function, Regulation.
- 10 credits overlap with MBV4230 – Eukaryotic Transcription Factors - Structures, Function, Regulation (continued).
- 10 credits overlap with MBV9230 – Eukaryotic Transcription Factors - Structures, Function, Regulation (continued).
Teaching
- Lectures
- Seminars with 15 minutes presentations of a scientific articles for the other students
- Group discussions to clarify or go deeper into certain aspects of le lectures
Attendance is mandatory for the first lecture. This also applies to those on the waiting list. You will lose your seat on the course if documentation for absence is not provided to the student administration studieinfo@ibv.uio.no prior to the first lecture.
Examination
- Final written exam, which counts 100?% towards the finale grade.?
This course has mandatory assignments that must be approved before you can sit the finale exam.
Optional oral exam depending on the number of participants.
It will also be counted as one of the three attempts to sit the exam for this course, if you sit the exam for one of the following courses: MBV4230 – Eukaryotic Transcription Factors - Structures, Function, Regulation (continued), MBV9230 – Eukaryotic Transcription Factors - Structures, Function, Regulation (continued), BIOS9912 – Eukaryotic Transcription Factors - Structures, Function, Regulation
Examination support material
No examination support material is allowed.
Language of examination
Subjects taught in English will only offer the exam paper in English. You may write your examination paper in Norwegian, Swedish, Danish or English.
Grading scale
Grades are awarded on a scale from A to F, where A is the best grade and F?is a fail. Read more about?the grading system.
Resit an examination
This course offers both postponed and resit of examination. Read more:
More about examinations at UiO
- Use of sources and citations
- Special exam arrangements due to individual needs
- Withdrawal from an exam
- Illness at exams / postponed exams
- Explanation of grades and appeals
- Resitting an exam
- Cheating/attempted cheating
You will find further guides and resources at the web page on examinations at UiO.